AYN

Research Associate-Pharmaceutical Sciences

University of Tennessee · Memphis, Tennessee, United States

Market Range: 11

Hiring Salary: $4,600.33 - $5,250.00/Monthly

THIS IS A GRANT-FUNDED POSITION FUNDED UNTIL JUNE 30, 2029.

JOB SUMMARY/ESSENTIAL JOB FUNCTIONS: Under the direction of an assigned supervisor, this position contributes to the small molecule drug development efforts and is focused on supporting pre-clinical drug development in animal models with specific focus on pharmacokinetic assessments, pharmacokinetic/pharmacodynamic modeling and simulation, application of pharmacometrics techniques and bioanalytical analysis using liquid-chromatography tandem mass spectrometry. Assists with mentoring graduate assistants, junior fellows, and research assistants in proper laboratory procedure and techniques.

- Works independently and collaboratively with research lab members to oversee and perform research work and provide scientific expertise/input on experimental planning for assigned projects.

- Plans, executes, documents, and analyzes in vitro and in vivo studies in pharmacokinetics and drug metabolism.

- Performs pharmacokinetic analyses and modeling using PK software, including Phoenix WinNonlin, NONMEM, and R.

- Develops and validates LC-MS/MS assays and analyzes biological samples.

- Assists in managing day-to-day lab activities for the assigned lab space.

- Performs basic material and lab equipment management functions, including ordering and stocking supplies.

- Assists in mentoring and training graduate students and junior postdocs in pharmacokinetic and bioanalytical techniques.

- Assists in gaining approval and adhering to compliance requirements for all performed experimentation.

- Presents research data at scientific meetings and conferences.

- Creates and updates thorough documentation of research activities and results, as well as lab-related safety policies; updates them as needed.

- Performs other related duties as assigned.

MINIMUM REQUIREMENTS:

EDUCATION: Ph.D. in pharmacology, pharmaceutical sciences, or related field of study. (TRANSCRIPT REQUIRED)

EXPERIENCE: Five (5) years of experience in pharmacokinetic research and LC-MS based analysis of small molecule drugs and metabolites in biological fluids, preferably related to anti-infective drug development with at least three (3) years as a Postdoctoral Scholar. Experience in maintaining and organizing lab space. (Minimum of five years of experience in animal-based pharmacology research preferred).

KNOWLEDGE, SKILLS, AND ABILITIES:

- Ability to work independently in planning, development, standardization, validation, and documentation of LC-MS/MS based assays including sample preparation for quantitation of drugs in biological samples.

- Demonstrated knowledge in handling and utilizing pharmacokinetic animal models.

- Knowledge and proficiency in population pharmacokinetic analyses techniques.

- Ability to communicate efficiently with colleagues from other disciplines and work as a highly motivated self-starter that is creative, result- and milestone-oriented.

- Ability to display high competency and experience in pharmacokinetic data analysis.

- Excellent oral and written communication and presentation skills in English are required.

- Knowledge and proficiency in clinical pharmacology and clinical research would be an advantage.

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