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Executive Assistant, supporting Chief Financial Officer

Olema Oncology · San Francisco, California, United States

Olema Oncology is a clinical-stage biopharmaceutical company committed to transforming the standard of care and improving outcomes for patients living with breast cancer and beyond. With our transformation into a fully integrated oncology company well underway, it’s an exciting time to be part of Team Olema.

Our lead product candidate, palazestrant, is a novel, orally available complete estrogen receptor antagonist (CERAN) and selective estrogen receptor degrader (SERD) currently in two pivotal Phase 3 clinical trials. We expect top-line data from OPERA-01, our ongoing Phase 3 trial of palazestrant as a monotherapy in patients with second- or third-line ER+/HER2- metastatic breast cancer (MBC), in Q1 2027 which, if positive, could lead to our first potential approval and commercial launch in 2028. OPERA-02, our Phase 3 trial of palazestrant in combination with ribociblib in patients with frontline ER+/HER2- MBC, is enrolling patients. Together with its mechanism of action, pharmacokinetic properties, and the potential to demonstrate activity in both ESR1 wild-type and mutant tumors, palazestrant could transform the metastatic breast cancer treatment paradigm and provide access to a $15 billion global market opportunity.

Our follow-on product candidate, OP-3136, is a potent KAT6 inhibitor with the potential to generate further value and meaningfully impact the metastatic breast cancer treatment landscape – particularly in combination with palazestrant. We recently presented encouraging Phase 1 monotherapy data from this program across multiple solid tumor types, are advancing patient enrollment in the ongoing combination arms in MBC, and expect to initiate a Phase 1 study of OP-3136 in combination with Bayer’s darolutamide in metastatic castration-resistant prostate cancer by the end of this year.

Aspiring to transform the metastatic treatment paradigm is an ambitious endeavor that requires a resolute approach to developing better therapies and passionate colleagues dedicated to helping the patients we serve feel better, longer. Team Olema possesses a deep commitment to a shared purpose, the sustained pursuit of excellence, cultivating the courage required to advance our programs, the drive to succeed, and a collective capacity for adaptability through learning, growth, and evolution. We are a small group of nimble self-starters who bring consistency in our quest for the extraordinary every single day.

If you’re ready to be part of a tenacious, courageous, agile, and growing team, join us in making a profound impact, together – for our patients, for your career, and for what’s beyond.

About the Role >>> Executive Assistant, supporting Chief Financial Officer

We are seeking a highly motivated, resourceful, and experienced Executive Assistant to support our Chief Financial Officer (CFO) and approximately 4–6 senior leaders within the organization. This is a highly visible role that requires exceptional organizational skills, sound judgment, discretion, communication excellence, and the ability to effectively manage multiple priorities in a fast-paced, collaborative environment.

The Executive Assistant will provide seamless administrative support across the CFO leadership team, balancing the needs of multiple executives while helping ensure day-to-day operations run smoothly. You will manage communications and coordinate activities with internal and key external parties, including investors and board members. You will be a trusted partner to the CFO and leadership team, as well as a valued member of the broader Executive Assistant team, collaborating with colleagues to provide outstanding support across the organization.

If you are organized, proactive, collaborative, and energized by supporting executives in a dynamic environment, particularly within the biotechnology or pharmaceutical industry this is a unique opportunity to contribute to our mission to develop innovative medicines for breast cancer and beyond.

This role is based in our San Francisco, CA office and requires an on-site presence four days per week.

Your work will primarily encompass:

Executive Support

- Provide day-to-day administrative support to the Chief Financial Officer (CFO) and approximately 4–6 senior leaders.

- Manage complex calendars for multiple executives, balancing competing priorities and coordinating meetings across internal and external stakeholders, including with investors and other key external parties.

- Coordinate meetings and events, including scheduling, conference room management, agendas, meeting materials, presentations, catering, and follow-up as needed.

- Coordinate external investor and scientific events, including venues, travel, accommodation, meals and other activities as necessary to ensure success.

- Arrange complex domestic and international travel, prepare detailed itineraries, and process expense reports through Concur.

- Ensure executives are well prepared for internal and external meetings by coordinating materials, presentations, and other supporting documentation.

- Serve as a primary point of contact for internal and external stakeholders, including members of the executive team, Board members, investors, consultants, business partners, and vendors.

Administrative Support & Team Collaboration

- Build strong partnerships with cross-functional teams to coordinate schedules, meetings, and other business activities.

- Partner closely with the Executive Assistant team to coordinate executive schedules, share best practices, and provide coverage as needed.

- Support leadership meetings, team meetings, offsites, executive visits, candidate interviews, and other special events.

- Process purchase orders, onboard vendors, and manage invoices and other administrative activities.

- Help maintain an organized, productive, and welcoming office environment, including conference room coordination and office support as needed.

- Handle confidential and sensitive information with professionalism, discretion, and sound judgment.

- Demonstrate flexibility in supporting changing business priorities and the evolving needs of the CFO's organization.

Ideal Candidate Profile >>>

A love of challenging, important work. We are a pragmatic team, driven to imagine and develop meaningful therapies for improving lives. All employees within our company play a unique and crucial role in our success, both in accomplishing our mission and building a positive company culture. As such, we are looking for someone with the right combination of knowledge, experience, and attributes for this role.

Knowledge

- Bachelor's degree strongly preferred.

- Advanced proficiency with Microsoft Office, including Outlook, Teams, Excel, and PowerPoint, as well as Zoom, Concur, and other business systems.

Experience

- 5+ years of experience supporting C-suite executives and senior leaders, including Vice Presidents and/or Senior Directors.

- Experience working in the biotechnology or pharmaceutical industry required.

- Experience supporting investor relations activities required.

- Demonstrated success managing multiple priorities in a fast-paced environment with changing business needs.

Attributes

- Exceptional organizational skills with strong attention to detail and the ability to manage complex calendars, meetings, travel, and logistics for multiple executives.

- Excellent written and verbal communication skills, and strong interpersonal skills to interface with key stakeholders.

- Strong judgment, problem-solving skills, and the ability to anticipate needs and proactively resolve issues.

- Ability to handle confidential information with the highest level of discretion.

- Positive, proactive, and resourceful with a strong sense of ownership and accountability.

- Flexible and adaptable, with the ability to manage multiple priorities and shifting business needs.

- Collaborative team player who builds st

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